I have been active in clinical research since I joined Indiana University School of Medicine in 1995 and my work has been published in Nature Medicine and New England Journal of Medicine among others. My Role as a leader of the Multiple Myeloma program has allowed me to participate in practice changing research using IMID's and Proteasome inhibitors. I have facilitated clinical research at IU Simon Cancer Center and IU School as the Medical director of clinical research and the associated dean for clinical research. I have focused on Myeloma and with the help of the IU Grand Challenge Grant we are putting together the infrastructure to support highly competitive team of researchers and conduct research aimed at preventing myeloma and improving the treatment of those suffering from the disease especially those with high-risk disease where both remission and survival durations are short. I am also active with the international Myeloma Foundation and the American Society of Hematology (ASH). My outside collaborations have focused on disease registries in order to understand the course of multiple myeloma in the real world. I am the chair of the steering committee of one registry (Connect MM) and member of the steering committee of another (Insight). My collaboration with ASH is focused on database harmonization and developing a large set of patients’ data housed in a one hub. This hub will provide the foundation for better understanding of the natural course of multiple myeloma.